N1-Me-Pseudo-UTP
Catalog No.: 270M-100
Size: 100 ul
Description
N1-Me-Pseudo-UTP is a modified nucleotide designed to be incorporated into mRNA via in vitro transcription (IVT). This modification reduces the innate immunogenicity of the mRNA while simultaneously enhancing expression efficiency by increasing ribosome loading. Experimental data demonstrate that, compared to Pseudo-UTP, N1-Me-Pseudo-UTP further improves mRNA expression levels in both cell cultures and murine models, while exhibiting lower immunogenicity. This product is a clear, colorless solution. It is primarily used in Oligonucleotide aptamers, Epigenetics and DNA damage research, In vitro transcription (IVT), Mutagenesis, and Photo-crosslinking studies.
Components
| Component | Size |
| N1-Me-Pseudo-UTP | 100 μl |
Product Details
Shipping condition: Blue ice / dry ice
Purity: ≥98% (HPLC)
Salt type: Na⁺
Buffer: 2 0 mM Tris-HCl
Concentration: 100 mM±5%
pH: 8.0±0.5
Solvent: Water
CAS number: 1428903-59-6 (free acid)
Molecular formula:
C₁₀H₁₇N₂O₁₅P₃ (free acid)；C₁₀H₁₃N₂Na₄O₁₅P₃ (Sodium salt)
Molecular weight: 498.17 g/mol (free acid)；586.09 g/mol (Sodium salt)
Note: Neither the raw materials nor the production process of this product involves any animal-derived components. This product is for research only.
Storage Condition
-20℃